The stirred tank reactor (STR) is the most widely used bioreactor type.
Applikon offers stainless steel pilot bioreactors for cell culture applications and stainless steel fermentors for microbial culture applications. The pilot scale bioreactors and fermentors are the transitional step between lab scale and production scale systems. The 316L stainless steel vessels are constructed according to the latest standard on hygienic processing and cGMP. The interior finish of the vessel is electro polished to Ra=0.4µm, while the exterior is mirror polished. The high grade surface finish secures a better cleanability. The systems are built according to the specific demands of a process using an extensive array of standard components. Because of the modularity and flexibility, the user can always adapt the systems to changed process demands. This results in low initial investment and low running costs.

The standard Pilot system range is separated in two different applications; cell or microbial fermentation. The cell bioreactors come in 30, 60 and 130 Ltr total volume. As the volume range for microbial application is: 20, 40, 70 and 140 Ltr total volume. Top and bottom drives (cell top only) are available in all sizes. The pilot system range is standard equipped with the magnetically coupled stirrer system that ensures long term contamination free operation.

Bioreactors and fermentors
Applikon Pilot Systems are designed for maximum flexibility in setting up. The reactor headplate only has entry ports and no welded pipes. This means that the systems can be completely customized for the user's application. When the application changes, the bioreactor set-up can easily be adapted to the changed process demands. Headplates are made of 316L stainles steel and all parts in the bioreactors have an electropolished finish that ensures reliable cleanability of the vessel and components. Vessels can be used up to 3.1 barg of overpressure.